Growth factor analogs
IGF-1 LR3 research peptide
IGF-1 LR3 is a recombinant analog of human insulin-like growth factor 1. It carries an arginine substitution at position 3 and a 13-amino-acid N-terminal extension, changes that greatly reduce binding to IGF-binding proteins. It is widely used as a cell-culture media supplement in biomanufacturing and cell biology.
For in-vitro laboratory research only. Not for human or veterinary use.
Specifications
- Compound
- IGF-1 LR3
- Also known as
- Long R3 IGF-I; LR3-IGF-1
- Class
- Growth factor analogs
- Length
- 83 amino acids
- Sequence
Human IGF-1 with Glu3→Arg substitution and 13-residue N-terminal extension- Molecular formula
- Recombinant protein
- Molecular weight
- approx. 9,111 Da
- Form
- Lyophilized powder, sealed vial
- Vial sizes
- 1mg
- Purity release standard
- ≥ 99.0% by HPLC-UV, identity by LC-MS
- Storage
- −20 °C, dry, protected from light
Lot release testing
Each IGF-1 LR3 lot is released only after it passes every assay below. Lots under 99.0% purity do not ship.
| Assay | Method | Release criterion |
|---|---|---|
| Purity | HPLC-UV | ≥ 99.0% |
| Net peptide content | Quantitative HPLC | ≥ 100% of label |
| Identity | LC-MS | Matches theoretical mass |
| Appearance | Visual | White lyophilized cake |
| Fentanyl screen | LC-MS/MS | Not detected |
| Heavy metals | ICP-MS | Within specification |
| Sterility | PCR | Not detected |
| Endotoxin | LAL | Within specification |
Frequently asked questions
What is IGF-1 LR3?
IGF-1 LR3 is a recombinant analog of human insulin-like growth factor 1. It carries an arginine substitution at position 3 and a 13-amino-acid N-terminal extension, changes that greatly reduce binding to IGF-binding proteins. It is widely used as a cell-culture media supplement in biomanufacturing and cell biology.
How is each IGF-1 LR3 lot tested?
Every lot is tested at an ISO/IEC 17025 accredited third-party laboratory against an eight-assay panel: HPLC-UV purity, quantitative net peptide content, LC-MS identity, appearance, a fentanyl screen, heavy metals by ICP-MS, sterility by PCR, and endotoxin by LAL. The certificate is published before the lot ships.
How do I verify the certificate for my IGF-1 LR3 vial?
Scan the QR code on the vial label to open the certificate for that exact lot, or search the lot number in the North Wall COA library.
Is IGF-1 LR3 for human use?
No. North Wall sells this compound solely for in-vitro laboratory research by qualified researchers aged 21 and over. It is not for human or veterinary use, and North Wall does not provide use, preparation, or dosing guidance.
Related reference pages
Molecular data: reported on each lot certificate of analysis. Lot-specific values appear on the certificate for each batch.